With both sides suffering defeat last time out, both will be looking to bounce back in this crucial clash at the weekend.
The Blues suffered a 31-25 defeat at the hands of London Scottish and Rosslyn Park were narrowly defeated by Cambridge 29-27.
Rosslyn Park, like Macclesfield are experiencing life in National League One for the first time after gaining promotion last year, and so far its been a steady start, after eleven games they have won five and lost six and sit ninth in the league. The Blues managed to claim a bonus point from Saturdays defeat and slip just one place to sixth.
Director of Rugby Geoff Wappet should once again name an unchanged starting fifteen, though Matt Owen and Ben Latham will be back after missing Saturdays defeat. Decisions will need to be made on the fitness of Richard Wigham after he picked up an injury and Tommy Taylor may return after turning out for the second team against Penrith.
The game promises to be a close encounter and both teams will be looking for a response after last weekends defeats though the Blues will believe they will have more than enough to see off the challenge of Rosslyn Park.